Radiation therapy for head and neck cancers in the elderly

Int J Radiat Oncol Biol Phys. 1990 Apr;18(4):819-23. doi: 10.1016/0360-3016(90)90403-7.

Abstract

Three hundred and thirty-one patients, aged more than 70 years, were treated for an upper aerodigestive tract carcinoma from 1978 to 1983. Larynx accounted for 28% of the primary sites, oropharynx for 27%, and the oral cavity for 16%. One-third of these patients had a contraindication to anesthesia. The treatment was consistent with our protocols in only half of the cases. Fifty-nine patients underwent a radiosurgical combination; 249 underwent an exclusive irradiation with a curative intent. Fifty-four patients underwent a palliative irradiation, which lead up to a "curative dose" in half of the cases. The immediate and long-term tolerance of the irradiation was good. The local control was 71% for patients treated with a curative intent and 19% for the palliatively irradiated patients. Five-year survival of the population was 33%. No significant relationship between age, general status, and the carcinologic outcome could be observed.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Carcinoma, Squamous Cell / epidemiology
  • Carcinoma, Squamous Cell / mortality
  • Carcinoma, Squamous Cell / radiotherapy*
  • Combined Modality Therapy
  • Female
  • France / epidemiology
  • Head and Neck Neoplasms / epidemiology
  • Head and Neck Neoplasms / mortality
  • Head and Neck Neoplasms / radiotherapy*
  • Humans
  • Male
  • Retrospective Studies
  • Survival Rate