Abstract
Glycopeptide-resistant Staphylococcus epidermidis (GRSE) strains are of increasing concern in bone and joint infections (BJIs). Using multilocus sequence typing and multilocus variable-number tandem repeat analysis, we show that BJI-associated GRSE strains are genetically diverse but arise from related, multiresistant hospital sequence types (STs), mostly ST2, ST5, and ST23.
MeSH terms
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Adult
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Aged
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Arthritis / epidemiology
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Arthritis / microbiology*
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Cluster Analysis
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Drug Resistance, Bacterial*
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Female
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Genetic Variation
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Genotype
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Glycopeptides / pharmacology*
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Humans
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Male
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Middle Aged
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Minisatellite Repeats
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Molecular Epidemiology
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Multilocus Sequence Typing
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Osteomyelitis / epidemiology
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Osteomyelitis / microbiology*
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Staphylococcal Infections / epidemiology
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Staphylococcal Infections / microbiology*
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Staphylococcus epidermidis / classification
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Staphylococcus epidermidis / drug effects*
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Staphylococcus epidermidis / genetics
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Staphylococcus epidermidis / isolation & purification