Two cases of hemolytic uremic syndrome caused by Streptococcus pneumoniae serotype 3, one being a vaccine failure

Scand J Infect Dis. 2013 May;45(5):411-4. doi: 10.3109/00365548.2012.737019. Epub 2012 Dec 28.

Abstract

We report two cases of Streptococcus pneumoniae-associated hemolytic uremic syndrome (SP-HUS) caused by serotype 3. One case occurred in an unvaccinated boy and 1 in a girl vaccinated with the 13-valent pneumococcal conjugate vaccine. SP-HUS must be considered in children, and conjugate vaccines may be less effective against serotype 3 than other serotypes.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • Hemolytic-Uremic Syndrome / microbiology*
  • Humans
  • Infant
  • Male
  • Pneumococcal Infections / microbiology*
  • Pneumococcal Vaccines / pharmacology
  • Streptococcus pneumoniae / isolation & purification*
  • Treatment Failure

Substances

  • 13-valent pneumococcal vaccine
  • Pneumococcal Vaccines