Abstract
We present the case of a patient with clinical signs of meningococcemia and negative bacterial culture. Microbiological diagnosis was possible only by testing with real time PCR technique the cerebrospinal fluid and blood samples. Both pathologic samples were positive for Neisseria meningitidis by this rapid and sensitive diagnostic method.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / therapeutic use
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Ceftriaxone / therapeutic use
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DNA, Bacterial / isolation & purification
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Diagnosis, Differential
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Exanthema / microbiology
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Humans
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Infant
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Male
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Meningism / microbiology
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Meningococcal Infections / blood
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Meningococcal Infections / cerebrospinal fluid
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Meningococcal Infections / diagnosis*
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Meningococcal Infections / drug therapy
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Neisseria meningitidis / genetics
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Neisseria meningitidis / isolation & purification*
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Predictive Value of Tests
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Real-Time Polymerase Chain Reaction* / methods
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Sensitivity and Specificity
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Treatment Outcome
Substances
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Anti-Bacterial Agents
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DNA, Bacterial
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Ceftriaxone