[Quality assurance of rapid on-site evaluation of CT-guided fine-needle aspiration cytology of lung nodules]

Orv Hetil. 2013 Jan 6;154(1):28-32. doi: 10.1556/OH.2013.29519.
[Article in Hungarian]

Abstract

Introduction: The methods available for the diagnosis of lung cancer include radiologic, cytologic and pathologic procedures.

Aims: The aim of this study was to determine the quality assurance of CT guided fine needle aspiration cytology of lung nodules.

Methods: Cytology results were rated to 4 categories (positive; suspicious; negative; not representative). All cytology reports were compared with the final histology diagnosis.

Results: A total of 128 patients underwent CT-guided percutaneous fine-needle aspiration biopsy cytology (63 males; 65 females; mean age 62.8 years). Smears were adequate in 99 cases and inadequate in 29 cases. The average diameter of the nodules was 3.28 cm. Thirty three (25.6%) of the cases were histologically verified and 2 falsely negative and 2 falsely positive cases were detected. The sensitivity and the positive predictive value were 88.8% and 88.8%, respectively. Pneumothorax developed in 7 (5.4%) cases.

Conclusion: These results suggest that CT-guided transthoracic fine needle aspiration cytology has a high diagnostic accuracy and an acceptable complication rate. The auditing valves of the results meet the proposed threshold values.

MeSH terms

  • Aged
  • Biopsy, Fine-Needle / methods*
  • Female
  • Humans
  • Image-Guided Biopsy / methods*
  • Lung / diagnostic imaging
  • Lung / pathology
  • Male
  • Middle Aged
  • Quality Assurance, Health Care*
  • Solitary Pulmonary Nodule / diagnostic imaging*
  • Solitary Pulmonary Nodule / pathology*
  • Tomography, X-Ray Computed*