Abstract
A putative underdiagnosis of clinical chikungunya virus infection in Dutch travelers to the Indian Ocean area was addressed by retrospective screening of all sera for which requested dengue virus serology was negative in the period 2007 to 2010. Evidence for a recent infection was observed in 6.5% of 107 patients, indicating a substantial underdiagnosis and the need for increased awareness among physicians.
© 2012 International Society of Travel Medicine.
MeSH terms
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Alphavirus Infections* / diagnosis
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Alphavirus Infections* / epidemiology
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Alphavirus Infections* / immunology
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Alphavirus Infections* / physiopathology
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Chikungunya Fever
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Chikungunya virus / isolation & purification*
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Dengue Virus / isolation & purification*
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Diagnosis, Differential
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Diagnostic Errors
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Humans
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Indian Ocean / epidemiology
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Netherlands / epidemiology
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Retrospective Studies
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Serologic Tests / methods*
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Severe Dengue* / diagnosis
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Severe Dengue* / epidemiology
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Severe Dengue* / immunology
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Severe Dengue* / physiopathology
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Travel / statistics & numerical data