Embolism and impaired washout: a possible explanation of border zone strokes in hypereosinophilic syndrome

Lago Aida; Vera Parkhutik; Jose Ignacio Tembl; Nuria Martín; Marina Frasquet; Luis Bataller

doi:10.1016/j.jns.2012.12.002

Embolism and impaired washout: a possible explanation of border zone strokes in hypereosinophilic syndrome

J Neurol Sci. 2013 Feb 15;325(1-2):162-4. doi: 10.1016/j.jns.2012.12.002. Epub 2013 Jan 3.

Authors

Lago Aida¹, Vera Parkhutik, Jose Ignacio Tembl, Nuria Martín, Marina Frasquet, Luis Bataller

Affiliation

¹ Department of Neurology, HU La Fe, Avda Peripheric Sud, s.n. Valencia, Spain. [email protected]

PMID: 23290568
DOI: 10.1016/j.jns.2012.12.002

Abstract

We describe 4 patients with stroke caused by hypereosinophilic syndrome, all of whom presented with border zone infarcts, and discuss the possible underlying mechanism. Cardioembolism (endomiocardial fibrosis) would coexist with impaired washout (perfusion disturbance due to high eosinophil count and/or eosinophil-derived substances), explaining the watershed characteristics of the infarcts.

Publication types

Case Reports

MeSH terms

Adult
Aged
Female
Humans
Hypereosinophilic Syndrome / complications
Hypereosinophilic Syndrome / diagnosis*
Intracranial Embolism / diagnosis*
Intracranial Embolism / etiology
Male
Middle Aged
Stroke / diagnosis*
Stroke / etiology