Abstract
Following a suspected case of hantavirus in a patientsuffering from acute kidney injury, rodents fromthe patient’s property in Yorkshire and the Humber,United Kingdom (UK) were screened for hantaviruses.Hantavirus RNA was detected via RT-PCR in two Rattusnorvegicus. Complete sequencing and phylogeneticanalysis established the virus as a Seoul hantavirus,which we have provisionally designated as strainHumber. This is the first hantavirus isolated from wildrodents in the UK and confirms the presence of a pathogenicSeoul virus in Europe.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acute Kidney Injury / diagnosis*
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Acute Kidney Injury / virology
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Animals
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Antibodies, Viral / blood*
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Communicable Diseases, Emerging / virology
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Disease Reservoirs
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Hantavirus Infections / diagnosis
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Hantavirus Infections / epidemiology*
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Hantavirus Infections / virology
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Humans
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Male
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Molecular Sequence Data
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Phylogeny
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RNA, Viral / analysis*
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RNA, Viral / genetics
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Rats
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Reverse Transcriptase Polymerase Chain Reaction
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Rodent Diseases
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Seoul virus / genetics
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Seoul virus / isolation & purification*
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Sequence Analysis, DNA
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United Kingdom / epidemiology
Substances
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Antibodies, Viral
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RNA, Viral