Abstract
The management of inflammatory bowel disease in the older patient extends beyond the gastrointestinal tract. Pre-existing comorbidities, polypharmacy, functional status and physical reserve can impact disease course, response to therapy and quality of life. Current therapeutic endpoints may not be as immediately applicable to the older IBD patient at higher risk for adverse outcomes. This review focuses on the latest studies addressing the natural history, clinical course and therapeutic outcomes among the older IBD cohort.
MeSH terms
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Adrenal Cortex Hormones / adverse effects*
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Adrenal Cortex Hormones / therapeutic use
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Aged
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Aged, 80 and over
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Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
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Colorectal Neoplasms / epidemiology*
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Comorbidity
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Drug Interactions
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Humans
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Immunosuppressive Agents / adverse effects
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Inflammatory Bowel Diseases / diagnosis*
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Inflammatory Bowel Diseases / drug therapy*
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Inflammatory Bowel Diseases / epidemiology
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Polypharmacy
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Skin Neoplasms / epidemiology*
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Tumor Necrosis Factor-alpha / antagonists & inhibitors
Substances
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Adrenal Cortex Hormones
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Anti-Inflammatory Agents, Non-Steroidal
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Immunosuppressive Agents
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Tumor Necrosis Factor-alpha