A patient has been described with an unusual variant of B-cell lymphoid leukemia. Specific morphology of leukemic cells (the presence of nuclear cleavage), initial and principal localization of the process in the bone marrow, as well as an original phenotype of malignant cells (CD5+, CD35+, CD37+ and CD38+) have given the grounds for the designation of this rare variant of leukemia as centrocytic.