MicroRNA in 2012: Biotherapeutic potential of microRNAs in rheumatic diseases

Yves-Marie Pers; Christian Jorgensen

doi:10.1038/nrrheum.2012.236

MicroRNA in 2012: Biotherapeutic potential of microRNAs in rheumatic diseases

Nat Rev Rheumatol. 2013 Feb;9(2):76-8. doi: 10.1038/nrrheum.2012.236. Epub 2013 Jan 15.

Authors

Yves-Marie Pers¹, Christian Jorgensen

Affiliation

¹ Clinical Immunology and Osteoarticular Diseases Therapeutic Unit, Lapeyronie University Hospital, 371 avenue du Doyen Gaston Giraud, 34295 Montpellier, France.

PMID: 23321608
DOI: 10.1038/nrrheum.2012.236

Abstract

A number of microRNAs have been implicated in the pathogenesis of various rheumatic diseases, and evidence in support of the therapeutic potential of microRNA-based strategies for these conditions is growing, as demonstrated by several new findings published in 2012.

Publication types

Review

MeSH terms

Animals
Biological Therapy / trends*
Disease Models, Animal
Humans
Mice
MicroRNAs / physiology*
Rheumatic Diseases / physiopathology*
Rheumatic Diseases / therapy*

Substances

MIRN194 microRNA, human
MIRN23a microRNA, human
MIRN323 microRNA, human
MicroRNAs