Acquired protein energy malnutrition in glutaric acidemia

Pediatr Dermatol. 2013 Jul-Aug;30(4):502-4. doi: 10.1111/pde.12067. Epub 2013 Jan 17.

Abstract

We report a case of acquired protein energy malnutrition with associated zinc deficiency in an 18-month-old boy with type 1 glutaric acidemia. Physical examination findings included generalized nonpitting edema, widespread desquamative plaques, and sparse hair with a reddish tinge. Laboratory abnormalities included low levels of zinc, albumin, alkaline phosphatase, and iron. A review of skin manifestations of nutritional deficiencies, specifically kwashiorkor, is presented, as well as the relatively new entity called acrodermatitis dysmetabolica.

Publication types

  • Case Reports

MeSH terms

  • Acrodermatitis / diagnosis
  • Amino Acid Metabolism, Inborn Errors / complications
  • Amino Acid Metabolism, Inborn Errors / diagnosis*
  • Biopsy
  • Brain Diseases, Metabolic / complications
  • Brain Diseases, Metabolic / diagnosis*
  • Dermatitis / diagnosis*
  • Dermatitis / etiology
  • Diagnosis, Differential
  • Glutaryl-CoA Dehydrogenase / deficiency*
  • Humans
  • Infant
  • Kwashiorkor / diagnosis
  • Male
  • Protein-Energy Malnutrition / diagnosis*
  • Protein-Energy Malnutrition / etiology
  • Zinc / deficiency*

Substances

  • Glutaryl-CoA Dehydrogenase
  • Zinc

Supplementary concepts

  • Glutaric Acidemia I