IncI1 plasmids associated with the spread of CMY-2, CTX-M-1 and SHV-12 in Escherichia coli of animal and human origin

Clin Microbiol Infect. 2013 May;19(5):E238-40. doi: 10.1111/1469-0691.12128. Epub 2013 Jan 17.

Abstract

Fourteen plasmids carrying blaCTX -M-1, blaSHV -12 or blaCMY -2 genes from Escherichia coli of both avian and human origin were analysed. IncI1 plasmids were largely predominant. Plasmid mutilocus sequence typing and comparative analysis revealed that the blaCMY -2 -ST12-IncI1 plasmids from avian E. coli were identical to those previously found in Salmonella from humans, but different to those associated with human E. coli. The IncI1-ST3 plasmids carrying blaCTX -M-1 or blaSHV -12 were related to those previously identified in avian E. coli, but different to those identified in human E. coli. Overall, no plasmids shared by E. coli of both origin (human/avian) were identified; however, further investigations are needed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Birds
  • Escherichia coli / classification
  • Escherichia coli / enzymology
  • Escherichia coli / genetics
  • Escherichia coli / isolation & purification*
  • Escherichia coli Infections / microbiology*
  • Escherichia coli Infections / veterinary*
  • Humans
  • Multilocus Sequence Typing
  • Plasmids / classification
  • Plasmids / isolation & purification*
  • Restriction Mapping
  • beta-Lactamases / genetics*

Substances

  • beta-lactamase CMY-2
  • beta-lactamase SHV-12
  • beta-lactamase TEM-3
  • beta-Lactamases