Effect of StentBoost imaging guided percutaneous coronary intervention on mid-term angiographic and clinical outcomes

Int J Cardiol. 2013 Sep 30;168(2):1479-84. doi: 10.1016/j.ijcard.2012.12.051. Epub 2013 Jan 16.

Abstract

Introduction: The gold standard for evaluating stent expansion after percutaneous coronary intervention (PCI) is intravascular ultrasound (IVUS). However, the routine use of this modality is costly and time consuming. StentBoost is a new imaging technique that improves fluoroscopy-based assessments of stent expansion. The purpose of this study was to evaluate the effect of StentBoost imaging-guided PCI on mid-term angiographic and clinical outcomes.

Methods and results: A total of 870 consecutive patients were recruited (mean age: 64.34 ± 11.61; men: 64.5%), all of whom underwent PCI with drug-eluting stents (DESs). The subjects were divided into a no StentBoost group (n=569 patients) and a StentBoost group (n=301 patients). The 6-month angiographic and 12-month clinical outcomes were compared between the two groups. At 1 month, clinical outcomes were similar between the two groups. At 6 months, the StentBoost group had significantly lower rates of late loss (0.32 ± 0.40 vs. 0.48 ± 0.59; p=0.005) and binary restenosis (1.2% vs. 8.3%; p=0.029) compared with the no-StentBoost group. At 12 months, StentBoost group had significantly lower the incidence of target lesion revascularization (TLR) (1.7% vs. 7%; p=0.034) and TLR-major adverse cardiac events (6% vs. 13.2%; p=0.037) compared with the no-StentBoost group.

Conclusion: We conclude that the routine clinical use of StentBoost during PCI can be useful, and results in better medium-term angiographic and clinical outcomes.

Keywords: Clinical outcomes; Percutaneous coronary intervention; StentBoost.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Coronary Angiography / standards*
  • Coronary Angiography / trends
  • Coronary Artery Disease / diagnostic imaging*
  • Coronary Artery Disease / surgery
  • Drug-Eluting Stents / standards*
  • Drug-Eluting Stents / trends
  • Female
  • Fluoroscopy / standards
  • Fluoroscopy / trends
  • Humans
  • Male
  • Middle Aged
  • Percutaneous Coronary Intervention / standards*
  • Percutaneous Coronary Intervention / trends
  • Prospective Studies
  • Registries
  • Retrospective Studies
  • Treatment Outcome
  • Ultrasonography, Interventional / standards*
  • Ultrasonography, Interventional / trends