Abstract
We report a case of mucocutaneous phaeohyphomycosis caused by Exophiala spinifera. Crusty plaques and nodules were major clinical features. Histological examination revealed brown yeast-like cells and hyphae. Mycological and molecular data identified E. spinifera as etiologic agent. Oral itraconazole was effective, which was in accordance with the results of in vitro susceptibility testing. We speculated that her pregnancy may play a role of risk factor in the infection by E. spinifera.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Administration, Oral
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Antifungal Agents / administration & dosage
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Exophiala / isolation & purification*
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Female
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Head / diagnostic imaging
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Histocytochemistry
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Humans
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Itraconazole / administration & dosage
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Microscopy
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Nasal Cavity / diagnostic imaging
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Nasal Mucosa / microbiology
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Nasal Mucosa / pathology*
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Phaeohyphomycosis / diagnosis*
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Phaeohyphomycosis / drug therapy
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Phaeohyphomycosis / microbiology
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Phaeohyphomycosis / pathology*
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Pregnancy
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Pregnancy Complications, Infectious / diagnosis*
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Pregnancy Complications, Infectious / drug therapy
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Pregnancy Complications, Infectious / microbiology
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Pregnancy Complications, Infectious / pathology*
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Radiography
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Skin / microbiology
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Skin / pathology*
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Treatment Outcome
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Young Adult
Substances
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Antifungal Agents
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Itraconazole