Abstract
We describe an outbreak of 5 osteoarticular infections among 24 daycare center attendees. Polymerase chain reaction revealed Kingella kingae in the joint fluid of 1 child and in 85% of throat samples from healthy contacts. Multilocus sequence typing performed on the joint fluid and carriage isolates identified an unique sequence type. Rifampin failed to eradicate K. kingae carriage.
MeSH terms
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Adult
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Anti-Bacterial Agents / therapeutic use
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Antibiotic Prophylaxis
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Arthritis, Infectious / drug therapy
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Arthritis, Infectious / epidemiology
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Arthritis, Infectious / microbiology
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Carrier State / microbiology
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Child Day Care Centers / statistics & numerical data
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Disease Outbreaks*
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Humans
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Infant
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Kingella kingae / genetics
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Kingella kingae / isolation & purification*
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Multilocus Sequence Typing
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Neisseriaceae Infections / drug therapy
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Neisseriaceae Infections / epidemiology*
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Neisseriaceae Infections / microbiology*
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Osteomyelitis / drug therapy
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Osteomyelitis / epidemiology
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Osteomyelitis / microbiology
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Pharynx / microbiology
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Polymerase Chain Reaction
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Rifampin / therapeutic use
Substances
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Anti-Bacterial Agents
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Rifampin