Lymphotoxin β receptor mediates caspase-dependent tumor cell apoptosis in vitro and tumor suppression in vivo despite induction of NF-κB activation

Carcinogenesis. 2013 May;34(5):1105-14. doi: 10.1093/carcin/bgt014. Epub 2013 Jan 24.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Apoptosis / physiology*
  • Caspases / genetics
  • Caspases / metabolism*
  • Cell Line, Tumor
  • Colonic Neoplasms / genetics
  • Colonic Neoplasms / metabolism
  • Colonic Neoplasms / pathology
  • Humans
  • Ligands
  • Lymphotoxin beta Receptor / genetics
  • Lymphotoxin beta Receptor / metabolism*
  • Mice
  • Mice, Inbred BALB C
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Mitochondria / genetics
  • Mitochondria / metabolism
  • NF-kappa B / genetics
  • NF-kappa B / metabolism*
  • Transplantation, Heterologous
  • Tumor Suppressor Proteins / genetics
  • Tumor Suppressor Proteins / metabolism*

Substances

  • Ligands
  • Lymphotoxin beta Receptor
  • NF-kappa B
  • Tumor Suppressor Proteins
  • Caspases