Imaging and percutaneous occlusion of a large aneurysm of the ductus arteriosus in an infant with Loeys-Dietz syndrome

Congenit Heart Dis. 2013 Nov-Dec;8(6):E192-5. doi: 10.1111/chd.12041. Epub 2013 Jan 28.

Abstract

Loeys-Dietz is a multisystem congenital syndrome that comprises craniofacial and cutaneous abnormalities as well as structural cardiac defects. One of its key pathological features is an aggressive widespread vasculopathy that can manifest as aortic or cerebral aneurysms, which is prone to dissection and rupture. We report a case of a large aneurysm of the ductus arteriosus in a patient with Loeys-Dietz syndrome, successfully occluded by interventional catheterization.

Keywords: Amplatzer; Ductal Aneurysm; Loeys-Dietz; Transcatheter Closure; losartan.

Publication types

  • Case Reports

MeSH terms

  • Aneurysm / complications
  • Aneurysm / diagnostic imaging*
  • Aneurysm / therapy*
  • Aortography / methods*
  • Cardiac Catheterization* / instrumentation
  • Ductus Arteriosus / diagnostic imaging*
  • Heart Diseases / complications
  • Heart Diseases / diagnostic imaging*
  • Heart Diseases / therapy*
  • Humans
  • Infant
  • Loeys-Dietz Syndrome / complications*
  • Loeys-Dietz Syndrome / diagnosis
  • Loeys-Dietz Syndrome / genetics
  • Male
  • Predictive Value of Tests
  • Tomography, X-Ray Computed*
  • Treatment Outcome