DNA methylation analysis in human cancer

Methods Mol Biol. 2013:980:131-56. doi: 10.1007/978-1-62703-287-2_7.

Abstract

The functional impact of aberrant DNA methylation and the widespread alterations in DNA methylation in cancer development have led to the development of a variety of methods to characterize the DNA methylation patterns. This chapter critiques and describes the major approaches to analyzing DNA methylation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA Methylation*
  • Epigenesis, Genetic
  • Epigenomics / methods*
  • Gene Expression Profiling
  • Humans
  • Neoplasms / genetics*
  • Sequence Analysis, DNA