Abstract
A novel method of electrochemical methylation-specific ligation detection reaction is first presented for simultaneous evaluation of multiple gene-methylation loci in a single-tube experiment without PCR amplification or restriction enzyme reaction.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Base Sequence
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DNA Methylation*
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Electrochemistry / methods*
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Genetic Loci / genetics*
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Ligases / metabolism*
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Molecular Sequence Data
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Oligodeoxyribonucleotides / genetics
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Oligodeoxyribonucleotides / metabolism
Substances
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Oligodeoxyribonucleotides
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Ligases