Efficacy and safety of a new superficial chemical peel using alpha-hydroxy acid, vitamin C and oxygen for melasma

J Cosmet Laser Ther. 2013 Feb;15(1):21-4. doi: 10.3109/14764172.2012.748199.

Abstract

Background: Facial skin pigmentary disorders can be resistant to conventional treatment. Superficial chemical peel is an effective and safe treatment in pigmentary problems including melasma, post-inflammatory hyperpigmentation and aging spots.

Objective: To assess the efficacy and safety of new superficial chemical peel (Melasma peel, Theraderm®), this is composed of alpha-hydroxy acid (AHAs), vitamin C and oxygen for melasma.

Methods: Twenty-five ethnic Korean patients (Fitzpatrick skin phototypes IV and V) with moderate to severe melasma were enrolled. The patients underwent four treatments at 1-2-week intervals for 8 weeks. Clinical improvement was evaluated on a 5-point scale by participants and by the same dermatologist, and adverse effects were checked during the study.

Results: Improvement in the degree of pigmentation, pores, and evenness were noted. Significant clinical improvement of hyperpigmentation was evident. No adverse effects were reported.

Conclusion: New superficial chemical peel using AHAs, vitamin C and oxygen is an effective and very safe treatment for melasma.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Ascorbic Acid / administration & dosage*
  • Asian People
  • Chemexfoliation / methods*
  • Face*
  • Female
  • Humans
  • Hydroxy Acids / administration & dosage*
  • Male
  • Melanosis / therapy*
  • Middle Aged
  • Patient Satisfaction
  • Republic of Korea

Substances

  • Hydroxy Acids
  • Ascorbic Acid