Metastatic complications of pericarditis and cardiac tamponade as a result of Staphylococcus aureus bacteremia developing during antimicrobial therapy

Hsin-I Shih; Chi-Jung Wu; Chia-Yu Chi; Hsin-Chun Lee; Tsai-Ling Yang Lauderdale; Yu-Tzu Lin; Chia-Chun Lin; Nan-Yao Lee; Chia-Ming Chang; Wen-Chien Ko

doi:10.2169/internalmedicine.52.8744

Metastatic complications of pericarditis and cardiac tamponade as a result of Staphylococcus aureus bacteremia developing during antimicrobial therapy

Intern Med. 2013;52(3):389-91. doi: 10.2169/internalmedicine.52.8744. Epub 2013 Feb 1.

Authors

Hsin-I Shih¹, Chi-Jung Wu, Chia-Yu Chi, Hsin-Chun Lee, Tsai-Ling Yang Lauderdale, Yu-Tzu Lin, Chia-Chun Lin, Nan-Yao Lee, Chia-Ming Chang, Wen-Chien Ko

Affiliation

¹ Department of Emergency Medicine, National Cheng Kung University, College of Medicine and Hospital, Taiwan.

PMID: 23370752
DOI: 10.2169/internalmedicine.52.8744

Abstract

Acute bacterial pericarditis is a rare but devastating complication of Staphylococcus aureus bacteremia (SAB). We herein describe the case of a previously healthy 81-year-old woman with SAB complicated by pericarditis that evolved into cardiac tamponade despite the administration of optimal antimicrobial therapy for 11 days. Three adhesion factor genes, fnbA, clfA and clfB, were identified in the causative isolate.

Publication types

Case Reports

MeSH terms

Adhesins, Bacterial / genetics
Aged
Aged, 80 and over
Anti-Bacterial Agents / therapeutic use
Bacteremia / complications*
Bacteremia / drug therapy
Bacteremia / microbiology
Cardiac Tamponade / etiology*
Female
Genes, Bacterial
Humans
Pericarditis / etiology*
Staphylococcal Infections / complications*
Staphylococcal Infections / drug therapy
Staphylococcal Infections / microbiology
Staphylococcus aureus / genetics
Staphylococcus aureus / isolation & purification
Staphylococcus aureus / pathogenicity

Substances

Adhesins, Bacterial
Anti-Bacterial Agents