Abstract
Novel guanylate cyclase stimulators are disclosed. Design, synthesis, SAR, and pharmacological profile of the compounds are discussed.
Copyright © 2013 Elsevier Ltd. All rights reserved.
MeSH terms
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Animals
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Guanylate Cyclase / chemistry
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Guanylate Cyclase / metabolism*
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Pyrazoles / chemical synthesis
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Pyrazoles / chemistry*
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Pyrazoles / pharmacology*
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Pyridines / chemical synthesis
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Pyridines / chemistry*
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Pyridines / pharmacology*
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Rats
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Stimulation, Chemical
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Structure-Activity Relationship
Substances
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Pyrazoles
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Pyridines
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Guanylate Cyclase