Orientation-controlled conjugation of haloalkane dehalogenase fused homing peptides to multifunctional nanoparticles for the specific recognition of cancer cells

Angew Chem Int Ed Engl. 2013 Mar 11;52(11):3121-5. doi: 10.1002/anie.201209662. Epub 2013 Feb 5.

Authors

Serena Mazzucchelli¹, Miriam Colombo, Paolo Verderio, Ewa Rozek, Francesco Andreata, Elisabetta Galbiati, Paolo Tortora, Fabio Corsi, Davide Prosperi

Affiliation

¹ Dipartimento di Scienze Biomediche e Cliniche Luigi Sacco, Università di Milano, Ospedale L. Sacco, Via G.B. Grassi 74, 20157 Milano, Italy. [email protected]

PMID: 23386453
DOI: 10.1002/anie.201209662

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Humans
Hydrolases / chemistry*
Hydrolases / metabolism
Immobilized Proteins / chemistry*
Immobilized Proteins / metabolism
Nanoparticles / chemistry*
Neoplasms / diagnosis*
Neoplasms / metabolism
Neoplasms / pathology*
Peptides / chemistry*
Peptides / metabolism
Recombinant Fusion Proteins / chemistry
Recombinant Fusion Proteins / metabolism
U937 Cells

Substances

Immobilized Proteins
Peptides
Recombinant Fusion Proteins
Hydrolases
haloalkane dehalogenase