Label-free second harmonic and hyper Rayleigh scattering with high efficiency

Opt Express. 2013 Jan 14;21(1):815-21. doi: 10.1364/OE.21.000815.

Abstract

We present a method to perform hyper Rayleigh scattering from aqueous solutions and second harmonic scattering measurements from unlabeled interfaces of liposomes and nanoparticles in dilute solutions. The water and interfacial response can be measured on a millisecond timescale, thus opening up the possibility to measure label-free time dependent transport processes in biological (membrane) systems.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Membrane / metabolism
  • Equipment Design
  • Gold / chemistry
  • Light
  • Liposomes / chemistry*
  • Metal Nanoparticles / chemistry
  • Nanoparticles / chemistry
  • Nanotechnology / methods
  • Polystyrenes / chemistry
  • Scattering, Radiation
  • Surface Properties
  • Water / chemistry

Substances

  • Liposomes
  • Polystyrenes
  • Water
  • Gold