Abstract
The Xpert GBS real-time PCR assay for the detection of group B streptococci (GBS) in antepartum screening samples was evaluated on amniotic fluid samples collected from 139 women with premature rupture of membrane at term. When any intrapartum positive result from the Xpert GBS or culture was considered a true positive, the sensitivities of the Xpert GBS and culture were 92.3% and 84.6%, respectively. This assay could enhance exact identification of candidates for intrapartum antibiotic prophylaxis.
Publication types
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Comparative Study
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Evaluation Study
MeSH terms
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Bacteriological Techniques / methods*
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Female
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Fetal Membranes, Premature Rupture*
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Humans
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Molecular Diagnostic Techniques / methods*
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Pregnancy
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Pregnancy Complications, Infectious / diagnosis*
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Prospective Studies
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Real-Time Polymerase Chain Reaction / methods*
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Streptococcal Infections / diagnosis*
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Streptococcus agalactiae / genetics
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Streptococcus agalactiae / growth & development
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Streptococcus agalactiae / isolation & purification*