Select Biosciences held its annual Genomics Research Asia 2012 Conference in the city of Daejeon, Republic of Korea, on 13-14 November 2012. This conference brought together an international roster of speakers and delegates primarily from Korea, but also from other parts of Asia, North America and Europe. The conference consisted of two tracks: first, RNAi, miRNA and epigenetics; and second, next-generation sequencing and advances in quantitative PCR. In this conference scene article, I report on selected presentations delivered in the RNAi, miRNA and epigenetics conference track and frame them into the broader trajectory adopted by these spaces.