Satiety, but not total PYY, Is increased with continuous and intermittent exercise

Obesity (Silver Spring). 2013 Oct;21(10):2014-20. doi: 10.1002/oby.20335. Epub 2013 May 25.

Abstract

Objective: This study determined the hormonal and subjective appetite responses to exercise (1-h continuous versus intermittent exercise throughout the day) in obese individuals.

Design and methods: Eleven obese subjects (>30 kg/m(2) ) underwent three 12-h study days: control condition [sedentary behavior (SED)], continuous exercise condition [(EX) 1-h exercise], and intermittent exercise condition [(INT) 12 hourly, 5-min bouts]. Blood samples (every 10 min) were measured for serum insulin and total peptide YY (PYY) concentrations, with ratings of appetite (visual analog scale [VAS): every 20 min]. Both total area under the curve (AUC), and subjective appetite ratings were calculated.

Results: No differences were observed in total PYY AUC between conditions, but hunger was reduced with INT (INT < EX; P < 0.05), and satiety was increased with both SED and INT conditions (INT > EX and SED > EX; P < 0.05). A correlation existed between the change in total PYY and insulin levels (r = -0.81; P < 0.05), and total PYY and satiety (r = 0.80; P < 0.05) with the EX condition, not the SED and INT conditions.

Conclusions: The total PYY response to meals is not altered over the course of a 12-h day with either intermittent or continuous exercise; however, intermittent exercise increased satiety and reduced hunger to a greater extent than continuous exercise in obese individuals.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Appetite / physiology
  • Blood Glucose / metabolism
  • Cross-Over Studies
  • Exercise / physiology*
  • Female
  • Humans
  • Insulin / blood
  • Male
  • Obesity / blood
  • Obesity / therapy
  • Peptide YY / blood*
  • Satiation / physiology*
  • Satiety Response / physiology
  • Young Adult

Substances

  • Blood Glucose
  • Insulin
  • Peptide YY