[Current aspects of Chlamydia trachomatis infection]

Presse Med. 2013 Apr;42(4 Pt 1):440-5. doi: 10.1016/j.lpm.2012.09.025. Epub 2013 Feb 16.
[Article in French]

Abstract

The number of detection and diagnosis of urogenital infections with Chlamydia trachomatis is increasing among both men and women. Three-quarters involve young people between 15 and 24 years. Infection, often asymptomatic, is more common in women. It is necessary to identify it to avoid complications.The number of rectal lymphogranuloma venereum (LGV) is also growing. The affected patients are homo/bisexuel men frequently co-infected with HIV. Nucleic acid amplification tests (NAATs) are the tests of choice to the diagnosis of C. trachomatis infection regardless of the clinical situation. Most of tests simultaneously detect C. trachomatis and Neisseria gonorrhoeae. The recommended treatment regimens for a non-complicated infection to C. trachomatis is azithromycin 1g orally in a single dose or doxycyline 100 mg orally twice a day for 7 days. Doxycyclin for 21 days remains the treatment of choice for LGV. Patients should be instructed to refer their sex partners for treatment.

Publication types

  • English Abstract
  • Review

MeSH terms

  • AIDS-Related Opportunistic Infections / diagnosis
  • AIDS-Related Opportunistic Infections / epidemiology
  • AIDS-Related Opportunistic Infections / transmission
  • Administration, Oral
  • Adolescent
  • Adult
  • Age Factors
  • Anti-Bacterial Agents / therapeutic use
  • Azithromycin / therapeutic use
  • Bisexuality
  • Chlamydia Infections / diagnosis
  • Chlamydia Infections / drug therapy
  • Chlamydia Infections / epidemiology*
  • Chlamydia Infections / transmission
  • Chlamydia trachomatis*
  • Cross-Sectional Studies
  • Doxycycline / therapeutic use
  • Female
  • France
  • Homosexuality, Male
  • Humans
  • Lymphogranuloma Venereum / diagnosis
  • Lymphogranuloma Venereum / drug therapy
  • Lymphogranuloma Venereum / epidemiology
  • Lymphogranuloma Venereum / transmission
  • Male
  • Sex Factors
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Azithromycin
  • Doxycycline