Surgical treatment of thumb basal joint arthritis is aimed at pain relief, restoration of pinch strength, and stability. We describe a variation of the abductor pollicus longus (APL) suspension arthroplasty originally described by Thompson, which maximizes strength of repair and is technically simple to perform. The technique consists of a trapeziectomy followed by resection of a slip of the APL and secure docking of the tendon into the base of the index metacarpal base. Stability is enhanced with a 3.0 mm biotenodesis screw. From March 2009 to September 2011, 50 patients were treated at our institution. Early results showed consistent pain relief, functional improvement, and minimal complications. The data support APL suspension arthroplasty with tenodesis screw fixation as a safe and effective treatment for CMC arthritis.