Conversion to the COBAS AmpliPrep/COBAS TaqMan CMV Test for management of CMV disease in transplant recipients

Bobbi S Pritt; Jeffrey J Germer; Eric Gomez-Urena; Callie J Bishop; Jayawant N Mandrekar; Cole L Irish; Joseph D C Yao

doi:10.1016/j.diagmicrobio.2013.01.014

Conversion to the COBAS AmpliPrep/COBAS TaqMan CMV Test for management of CMV disease in transplant recipients

Diagn Microbiol Infect Dis. 2013 Apr;75(4):440-2. doi: 10.1016/j.diagmicrobio.2013.01.014. Epub 2013 Feb 19.

Authors

Bobbi S Pritt¹, Jeffrey J Germer, Eric Gomez-Urena, Callie J Bishop, Jayawant N Mandrekar, Cole L Irish, Joseph D C Yao

Affiliation

¹ Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

PMID: 23428458
DOI: 10.1016/j.diagmicrobio.2013.01.014

Abstract

Testing of clinical plasma specimens by the COBAS AmpliPrep/COBAS TaqMan CMV Test (CAP/CTM CMV), COBAS AMPLICOR CMV MONITOR Test (CAM CMV), and a laboratory-developed assay using analyte-specific reagents (LC CMV) demonstrated substantial result bias for CAP/CTM CMV versus CAM CMV (r = 0.436) and CAP/CTM CMV versus LC CMV (r = 0.773).

Publication types

Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Cytomegalovirus Infections / diagnosis*
Cytomegalovirus Infections / virology
Humans
Molecular Diagnostic Techniques / methods*
Real-Time Polymerase Chain Reaction / methods*
Transplantation*
Viral Load / methods*
Virology / methods*