Can liberating p53 from E6 free patients from HPV-related head and neck tumors?

Cell Cycle. 2013 Mar 15;12(6):868. doi: 10.4161/cc.24101. Epub 2013 Feb 26.

Author

Affiliation

¹ Laboratoire de Biologie Tumorale, Centre Régional de Lutte Contre le Cancer Paul Strauss, Strasbourg, France. [email protected]

No abstract available

Keywords: Bortezomib; E6; HPV; Head and Neck Squamous Cell Carcinoma; apoptosis; cell cycle arrest; p21; p53.

Publication types

Comment

MeSH terms

Carcinoma, Squamous Cell / metabolism*
Cyclin-Dependent Kinase Inhibitor p21 / metabolism*
Head and Neck Neoplasms / metabolism*
Humans
Oncogene Proteins, Viral / genetics*
Papillomavirus E7 Proteins / genetics*
Repressor Proteins / genetics*
Squamous Cell Carcinoma of Head and Neck
Tumor Suppressor Protein p53 / metabolism*

Substances

Cyclin-Dependent Kinase Inhibitor p21
E6 protein, Human papillomavirus type 16
Oncogene Proteins, Viral
Papillomavirus E7 Proteins
Repressor Proteins
Tumor Suppressor Protein p53
oncogene protein E7, Human papillomavirus type 16