Abstract
We present estimates of influenza vaccine effectiveness (VE) in Navarre, Spain, in the early 2012/13 season, which was dominated by influenza B. In a population-based cohort using electronic records from physicians, the adjusted VE in preventing influenzalike illness was 32% (95% confidence interval (CI): 15 to 46). In a nested test-negative case-control analysis the adjusted VE in preventing laboratory-confirmed influenza was 86% (95% CI: 45 to 96). These results suggest a high protective effect of the vaccine.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Case-Control Studies
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Child
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Child, Preschool
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Female
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Hospitalization
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Humans
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Incidence
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Influenza A Virus, H1N1 Subtype / immunology*
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Influenza A Virus, H1N1 Subtype / isolation & purification
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Influenza A Virus, H3N2 Subtype / immunology*
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Influenza A Virus, H3N2 Subtype / isolation & purification
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Influenza A Virus, H3N8 Subtype / immunology*
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Influenza A Virus, H3N8 Subtype / isolation & purification
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Influenza B virus / immunology*
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Influenza B virus / isolation & purification
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Influenza Vaccines / administration & dosage*
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Influenza Vaccines / immunology
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Influenza, Human / epidemiology
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Influenza, Human / prevention & control*
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Influenza, Human / virology
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Logistic Models
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Male
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Middle Aged
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Population Surveillance
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Prospective Studies
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Seasons
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Spain / epidemiology
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Treatment Outcome
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Vaccination / statistics & numerical data
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Young Adult