An assessment of feeding jejunostomy tube placement at the time of resection for gastric adenocarcinoma

J Surg Oncol. 2013 Jun;107(7):728-34. doi: 10.1002/jso.23324. Epub 2013 Feb 28.

Abstract

Background: Feeding jejunostomy tubes (J-tube) are often placed during gastrectomy for cancer to decrease malnutrition and promote delivery of adjuvant therapy. We hypothesized that J-tubes actually are associated with increased complications and do not improve nutritional status nor increase rates of adjuvant therapy.

Methods: One hundred thirty-two patients were identified from a prospectively maintained database that underwent gastric resection for gastric adenocarcinoma between 1/00 and 3/11 at one institution. Pre- and postoperative nutritional status and relevant intraoperative and postoperative parameters were examined.

Results: Median age was 64 years (range 23-85). Forty-six (35%) underwent a total and 86 (65%) a subtotal gastrectomy. J-tubes were placed in 66 (50%) patients, 34 of whom underwent a subtotal and 32 a total gastrectomy. Preoperative nutritional status was similar between J-tube and no J-tube groups as measured by serum albumin (3.5 vs. 3.4 g/dL). Tumor grade, T, N, and overall stage were similar between groups. J-tube placement was associated with increased postop complications (59% vs. 41%, P = 0.04) and infectious complications (36% vs. 17%, P = 0.01), of which majority were surgical site infections. J-tubes were associated with prolonged length of stay (13 vs. 11 days; P = 0.05). There was no difference in postoperative nutritional status as measured by 30, 60, and 90-day albumin levels and the rate of receiving adjuvant therapy was similar between groups (J-tube: 61%, no J-tube: 53%, P = 0.38). Multivariate analyses revealed J-tubes to be associated with increased postop complications (HR: 4.8; 95% CI: 1.3-17.7; P = 0.02), even when accounting for tumor stage and operative difficulty and extent. Subset analysis revealed J-tubes to have less associated morbidity after total gastrectomy.

Conclusion: J-tube placement after gastrectomy for gastric cancer may be associated with increased postoperative complications with no demonstrable advantage in receiving adjuvant therapy. Routine use of J-tubes after subtotal gastrectomy may not be justified, but may be selectively indicated in patients undergoing total gastrectomy. A prospective trial is needed to validate these results.

Publication types

  • Comparative Study

MeSH terms

  • Adenocarcinoma / ethnology
  • Adenocarcinoma / surgery*
  • Adult
  • Aged
  • Aged, 80 and over
  • Enteral Nutrition*
  • Female
  • Gastrectomy* / adverse effects
  • Gastrectomy* / methods
  • Humans
  • Intubation, Gastrointestinal / adverse effects
  • Intubation, Gastrointestinal / methods
  • Jejunostomy* / adverse effects
  • Jejunostomy* / statistics & numerical data
  • Length of Stay
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Neoplasm Staging
  • Nutritional Status
  • Odds Ratio
  • Patient Readmission
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / etiology
  • Reoperation
  • Retrospective Studies
  • Risk Factors
  • Serum Albumin / metabolism
  • Stomach Neoplasms / ethnology
  • Stomach Neoplasms / surgery*
  • Treatment Failure

Substances

  • Serum Albumin