[Chemical constituents from Coptis chinensis]

Zhong Yao Cai. 2012 Sep;35(9):1438-41.
[Article in Chinese]

Abstract

Objective: To study the chemical constituents of Coptis chinensis.

Methods: The compounds were separated and purified by column chromatography and their structures were identified by spectroscopic methods.

Results: Seven compounds were isolated from the chloroform extract of Coptis chinensis, whose structures were determined as worenine (1),8,9-dihydroxy-1,5,6, 10b-tetrahydro-2H-pyrrolo[2,1 -alpha] isoquinolin-3-one (2),(+/-) -5,5'-dimethoxy-lariciresinol (3),3,4-dihydroxy-phenylethylalcohol(4), methyl-5-O-feruloylquinate (5), ethyl-5-O- feruloylquinate (6), apocynol (7).

Conclusion: Compounds (3) is isolated from this genus for the first time, compounds (5), (6), (7) are isolated from this plant for the first time.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzodioxoles / chemistry
  • Benzodioxoles / isolation & purification
  • Chloroform / chemistry
  • Chromatography, High Pressure Liquid
  • Coptis / chemistry*
  • Ethanol / chemistry
  • Guaiacol / analogs & derivatives*
  • Guaiacol / chemistry
  • Guaiacol / isolation & purification
  • Lignans / chemistry
  • Lignans / isolation & purification*
  • Molecular Structure
  • Quinolizines / chemistry
  • Quinolizines / isolation & purification
  • Rhizome / chemistry

Substances

  • 9,9'- O-di-(E)-feruloyl-meso-5,5'-dimethoxysecoisolariciresinol
  • Benzodioxoles
  • Lignans
  • Quinolizines
  • apocynol
  • Ethanol
  • Guaiacol
  • Chloroform
  • worenine