Lack of nasal carriage of novel corona virus (HCoV-EMC) in French Hajj pilgrims returning from the Hajj 2012, despite a high rate of respiratory symptoms

Clin Microbiol Infect. 2013 Jul;19(7):E315-7. doi: 10.1111/1469-0691.12174. Epub 2013 Mar 2.

Abstract

A cohort of 154 French Hajj pilgrims participating in the 2012 Hajj were systematically sampled with nasal swabs prior to returning to France, and screened for the novel HCoV-EMC coronavirus by two real-time RT-PCR assays. Despite a high rate of respiratory symptoms (83.4%), including 41.0% influenza-like illness, no case of HCoV-EMC infection was detected. Despite the fact that zoonotic transmission was suspected in the first few cases, a recent family cluster in the Kingdom of Saudi Arabia suggests that the virus might show at least limited spread from person to person, which justifies continuing epidemiological surveillance.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Animals
  • Carrier State / virology*
  • Cohort Studies
  • Coronavirus / isolation & purification*
  • Coronavirus Infections / virology*
  • Crowding*
  • Female
  • France
  • Humans
  • Male
  • Middle Aged
  • Nasal Cavity / virology*
  • Respiratory Tract Infections / epidemiology
  • Respiratory Tract Infections / virology*
  • Saudi Arabia
  • Travel*
  • Young Adult