[Description of patients with confirmed influenza A(H1N1)pdm09 admitted to an intensive care unit and identification of severity risk factors]

Med Mal Infect. 2013 Feb;43(2):81-4. doi: 10.1016/j.medmal.2013.01.016. Epub 2013 Feb 28.
[Article in French]

Abstract

Objective: The authors had for objective to describe patients with confirmed influenza A(H1N1)pdm09 admitted to an intensive care unit (ICU) in a university hospital and to identify risk factors correlated with the severity of the disease.

Design: A prospective study was conducted in an university hospital during the A(H1N1)pdm09 influenza pandemic. Severe laboratory confirmed cases (admitted to an ICU) were described and compared with non-severe confirmed cases (not admitted to an ICU).

Results: Sixty-nine patients were included; 36 (52%) were 15 to 44 years of age. Sixteen (23%) cases were defined as severe, ten of these (63%) concerned patients 45 to 64 years of age. The independent factors associated with severity were: a history of heart disease, obesity, and tobacco abuse.

Conclusions: This work reinforces the need to identify and protect groups at risk of severe outcomes.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Comorbidity
  • Disease Outbreaks*
  • Female
  • France / epidemiology
  • Heart Diseases / epidemiology
  • Hospitals, University / statistics & numerical data
  • Humans
  • Influenza A Virus, H1N1 Subtype / isolation & purification*
  • Influenza, Human / epidemiology*
  • Influenza, Human / virology
  • Intensive Care Units*
  • Male
  • Middle Aged
  • Obesity / epidemiology
  • Prospective Studies
  • Risk Factors
  • Smoking / epidemiology
  • Young Adult