Abstract
AL amyloidosis presenting as a solitary mediastinal mass is a rare occurrence, with only a few cases reported in the literature. We describe a case of a man presenting with a mediastinal mass diagnosed as amyloidosis, confirmed by mass spectrometry to consist of lambda light chains. Here we review the literature and discuss treatment options for this rare entity.
MeSH terms
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Aged
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Amyloid / metabolism*
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Amyloidosis / complications*
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Amyloidosis / diagnosis
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Amyloidosis / metabolism
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Humans
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Immunoglobulin lambda-Chains / metabolism*
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Male
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Mediastinal Diseases / diagnosis
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Mediastinal Diseases / etiology*
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Mediastinal Diseases / metabolism
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Review Literature as Topic
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Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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Tomography, X-Ray Computed
Substances
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Amyloid
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Immunoglobulin lambda-Chains
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amyloid L, human