Nutrition assessment and support in children with end-stage liver disease

Nutr Clin Pract. 2013 Jun;28(3):317-29. doi: 10.1177/0884533612474043. Epub 2013 Mar 6.

Abstract

Malnutrition is a treatable complication in children with end-stage liver disease (ESLD). Biliary atresia and other cholestatic disorders are the most frequent cause of ESLD in children. No single variable provides adequate information about nutrition status, yet effective nutrition support is the one intervention known to improve pre- and posttransplant outcomes. A proactive approach consisting of screening anthropometry interpreted using appropriate growth references, recognition of clinical manifestations associated with micronutrient deficiency, and timely aggressive nutrition support is of a paramount importance to maximize anabolism and optimize outcomes. This article presents the principles of nutrition assessment, intervention, and monitoring in children with ESLD.

Keywords: end-stage liver disease; enteral nutrition; growth; liver diseases; nutrition assessment; nutritional status; nutritional support; pediatrics; vitamins.

Publication types

  • Review

MeSH terms

  • Body Mass Index
  • Body Weight
  • Child, Preschool
  • Dietary Carbohydrates / administration & dosage
  • Dietary Fats / administration & dosage
  • Dietary Proteins / administration & dosage
  • End Stage Liver Disease / complications
  • End Stage Liver Disease / diet therapy*
  • End Stage Liver Disease / physiopathology
  • Humans
  • Infant
  • Malnutrition / complications
  • Malnutrition / diet therapy
  • Malnutrition / physiopathology
  • Micronutrients / administration & dosage
  • Nutrition Assessment*
  • Nutritional Requirements
  • Nutritional Status
  • Nutritional Support / methods*
  • Practice Guidelines as Topic

Substances

  • Dietary Carbohydrates
  • Dietary Fats
  • Dietary Proteins
  • Micronutrients