Abstract
A babygirl, aged six weeks, was hospitalized for rectal prolapse and isolated constipation. The investigation revealed a neuroblastoma (NB) inducing a medullar compression responsible for the sphincter disorders. NB is second among pediatric solid tumors, but is the most frequent cancer among infants. Its diagnosis is difficult because of its rarity and the variety of its symptoms. A new staging, based on imaging, has recently been proposed by the International Neuroblastoma Risk Group. With the exception of its localized, easily resectable forms, NB is best treated by chemotherapy.
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Biomarkers, Tumor / blood
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Carboplatin / administration & dosage
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Constipation / etiology
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Dexamethasone / administration & dosage
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Diagnosis, Differential
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Etoposide / administration & dosage
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Female
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Follow-Up Studies
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Humans
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Infant
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Inpatients
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Kidney Neoplasms / blood
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Kidney Neoplasms / complications
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Kidney Neoplasms / diagnosis
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Kidney Neoplasms / drug therapy
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Kidney Neoplasms / secondary*
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Lumbar Vertebrae / diagnostic imaging
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Neoplasm Staging
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Neuroblastoma / blood
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Neuroblastoma / complications*
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Neuroblastoma / diagnosis*
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Neuroblastoma / drug therapy
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Neuroblastoma / secondary
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Paraparesis / etiology
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Peripheral Nervous System Neoplasms / blood
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Peripheral Nervous System Neoplasms / complications
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Peripheral Nervous System Neoplasms / diagnosis*
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Peripheral Nervous System Neoplasms / drug therapy
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Peripheral Nervous System Neoplasms / pathology
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Phosphopyruvate Hydratase / blood
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Radiography
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Rectal Prolapse / etiology
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Spinal Nerve Roots / diagnostic imaging
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Spinal Nerve Roots / pathology*
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Treatment Outcome
Substances
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Biomarkers, Tumor
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Etoposide
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Dexamethasone
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Carboplatin
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Phosphopyruvate Hydratase