Detection of Hg2+ and F- ions by using fluorescence switching of quantum dots in an Au-cluster-CdTe QD nanocomposite

Chemistry. 2013 May 3;19(19):5980-7. doi: 10.1002/chem.201203576. Epub 2013 Mar 11.

Abstract

A single probe of an Au nanocluster-CdTe quantum dots nanocomposite has been developed by using tripeptide-capped CdTe quantum dots (QD) and bovine serum albumin (BSA) protein-conjugated Au25 nanocluster (NC) for detection of both Hg(2+) ion and F(-) ion. The formation of Au-NC-CdTe QD nanocomposite has been confirmed by TEM, steady state and time resolved spectroscopy, CD and FTIR studies. A significant signal off (74 % PL quenching at 553 nm) phenomenon of this nanocomposite is observed in presence of 6.56×10(-7) M Hg(2+) ion, due to salt-induced aggregation. However, a dramatic PL enhancement (128 %) of the Au-NC-CdTe QD nanocomposite is observed in presence of 8.47×10(-7) M F(-) anion. The calculated limit of detections (LOD) of Hg(2+) ion concentration and F(-) ion concentration are found to be 9 and 117 nM, respectively, which are within the safety range set by the United States Environment Protection Agency. Thus, the simple Au-NC-CdTe QD optical-based sensor is very useful to detect both toxic cations and anions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cadmium Compounds / chemistry*
  • Cattle
  • Fluorescence
  • Fluorides / chemistry*
  • Gold / chemistry*
  • Ions / chemistry*
  • Limit of Detection
  • Mercury / chemistry*
  • Nanocomposites / chemistry*
  • Quantum Dots / chemistry*
  • Serum Albumin, Bovine / chemistry*
  • Spectrometry, Fluorescence / methods
  • Tellurium / chemistry*

Substances

  • Cadmium Compounds
  • Ions
  • Serum Albumin, Bovine
  • Gold
  • Mercury
  • Tellurium
  • Fluorides