Lack of association between DISC1 polymorphisms and risk of schizophrenia in a Korean population

Psychiatry Res. 2013 Jul 30;208(2):189-90. doi: 10.1016/j.psychres.2013.01.029. Epub 2013 Mar 14.

Abstract

The DISC1 gene is considered to be a strong candidate gene for the development of schizophrenia. This study examines the association of DISC1 polymorphisms with schizophrenia in a Korean population. Although we fail to discover convincing evidence that DISC1 affects schizophrenia development, our findings may be useful for further genetic studies.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Asian People / genetics*
  • Female
  • Genetic Association Studies
  • Genetic Predisposition to Disease / genetics*
  • Humans
  • Male
  • Middle Aged
  • Nerve Tissue Proteins / genetics*
  • Polymorphism, Single Nucleotide / genetics
  • Republic of Korea
  • Schizophrenia / genetics*

Substances

  • DISC1 protein, human
  • Nerve Tissue Proteins