Preparation and characterization of multi-walled carbon nanotube/hydroxyapatite nanocomposite film dip coated on Ti-6Al-4V by sol-gel method for biomedical applications: an in vitro study

Mater Sci Eng C Mater Biol Appl. 2013 May 1;33(4):2002-10. doi: 10.1016/j.msec.2013.01.014. Epub 2013 Jan 26.

Abstract

In the present research, the introduction of multi-walled carbon nanotubes (MWCNTs) into the hydroxyapatite (HA) matrix and dip coating of nanocomposite on titanium alloy (Ti-6Al-4V) plate was conducted in order to improve the performance of the HA-coated implant via the sol-gel method. The structural characterization and electron microscopy results confirmed well crystallized HA-MWCNT coating and homogenous dispersion of carbon nanotubes in the ceramic matrix at temperatures as low as 500 °C. The evaluation of the mechanical properties of HA and HA/MWCNT composite coatings with different weight percentages of MWCNTs showed that the addition of low concentrations of MWCNTs (0.5 and 1 wt.%) had improved effect on the mechanical properties of nanocomposite coatings. Moreover, this in vitro study ascertained the biocompatibility of the prepared sol-gel-derived HA/MWCNT composite coatings.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alloys
  • Biomedical Technology
  • Coated Materials, Biocompatible / pharmacology*
  • Durapatite / pharmacology*
  • Elastic Modulus / drug effects
  • Hardness
  • Humans
  • Materials Testing*
  • Mesenchymal Stem Cells / cytology
  • Mesenchymal Stem Cells / drug effects
  • Mesenchymal Stem Cells / ultrastructure
  • Microscopy, Atomic Force
  • Nanocomposites / chemistry*
  • Nanocomposites / ultrastructure
  • Nanotubes, Carbon / chemistry*
  • Nanotubes, Carbon / ultrastructure
  • Phase Transition*
  • Spectroscopy, Fourier Transform Infrared
  • Static Electricity
  • Titanium / pharmacology*
  • X-Ray Diffraction

Substances

  • Alloys
  • Coated Materials, Biocompatible
  • Nanotubes, Carbon
  • titanium alloy (TiAl6V4)
  • Durapatite
  • Titanium