Abstract
Schizophyllum commune (n = 30) showed lowest geometric mean MICs of isavuconazole (0.19 μg/ml), itraconazole (0.2 μg/ml), voriconazole (0.24 μg/ml), and amphotericin B (0.29 μg/ml) and high geometric mean MICs of fluconazole (19.39 μg/ml) and flucytosine (17.28 μg/ml). Five cases (of 8) of allergic bronchopulmonary mycosis that were treated with itraconazole had no recrudescence after 6 to 24 months of follow-up. One case each of invasive pulmonary mycosis and fungal ball were treated successfully with voriconazole and itraconazole.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amphotericin B / pharmacology
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Amphotericin B / therapeutic use
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Antifungal Agents* / pharmacology
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Antifungal Agents* / therapeutic use
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Humans
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Invasive Pulmonary Aspergillosis / drug therapy*
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Invasive Pulmonary Aspergillosis / microbiology
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Itraconazole / pharmacology
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Itraconazole / therapeutic use
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Mycoses / drug therapy*
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Mycoses / microbiology
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Pyrimidines / pharmacology
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Pyrimidines / therapeutic use
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Schizophyllum / classification
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Schizophyllum / drug effects*
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Schizophyllum / genetics
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Sequence Analysis, DNA
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Treatment Outcome
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Triazoles / pharmacology
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Triazoles / therapeutic use
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Voriconazole
Substances
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Antifungal Agents
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Pyrimidines
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Triazoles
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Itraconazole
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Amphotericin B
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Voriconazole
Associated data
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GENBANK/KC414792
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GENBANK/KC414793
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GENBANK/KC414794
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GENBANK/KC414795
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