Pathological changes in the biochemical profile of the liver in atherosclerosis and diabetes assessed by Raman spectroscopy

Kamila Kochan; Katarzyna M Marzec; Katarzyna Chruszcz-Lipska; Agnieszka Jasztal; Edyta Maslak; Hanna Musiolik; Stefan Chłopicki; Malgorzata Baranska

doi:10.1039/c3an00216k

Pathological changes in the biochemical profile of the liver in atherosclerosis and diabetes assessed by Raman spectroscopy

Analyst. 2013 Jul 21;138(14):3885-90. doi: 10.1039/c3an00216k.

Authors

Kamila Kochan¹, Katarzyna M Marzec, Katarzyna Chruszcz-Lipska, Agnieszka Jasztal, Edyta Maslak, Hanna Musiolik, Stefan Chłopicki, Malgorzata Baranska

Affiliation

¹ Faculty of Chemistry, Jagiellonian University, Ingardena 3, 30-060 Krakow, Poland.

PMID: 23515303
DOI: 10.1039/c3an00216k

Abstract

Raman microspectroscopic imaging has been utilized for the investigation of pathological changes in the liver induced by diabetes and atherosclerosis.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Apolipoproteins E / physiology
Atherosclerosis / metabolism
Atherosclerosis / pathology*
Biomarkers / analysis*
Diabetes Mellitus, Experimental / metabolism
Diabetes Mellitus, Experimental / pathology*
Heme / metabolism
Lipids / analysis*
Liver / metabolism
Liver / pathology*
Mice
Mice, Inbred C57BL
Mice, Knockout
Receptors, LDL / physiology
Spectrum Analysis, Raman / methods*
Vitamin A / metabolism

Substances

Apolipoproteins E
Biomarkers
Lipids
Receptors, LDL
Vitamin A
Heme