Abstract
Histoplasmosis is an endemic fungal infection that causes no symptoms or minor self-limited illnesses in most cases. Severe forms are commonly reported in patients with immunodeficiency disorders; histoplasmosis is considered to be an opportunistic infection in patients with AIDS. We report a case of disseminated histoplasmosis in a patient with no induced active suppression of the immune response. The infection was fulminant, and antifungal treatment was delayed because of a misdiagnosis of tuberculosis.
Copyright © 2012 Elsevier Masson SAS. All rights reserved.
MeSH terms
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Adult
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Amphotericin B / therapeutic use
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Antifungal Agents / therapeutic use
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Antitubercular Agents / therapeutic use
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Brazil / ethnology
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Bronchoalveolar Lavage Fluid / microbiology
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Delayed Diagnosis
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Diagnostic Errors*
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Disseminated Intravascular Coagulation / etiology
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Fatal Outcome
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French Guiana
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HIV Seronegativity
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Histoplasma / isolation & purification
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Histoplasmosis / complications
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Histoplasmosis / diagnosis*
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Histoplasmosis / drug therapy
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Humans
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Immunocompetence
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Lung Diseases, Fungal / complications
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Lung Diseases, Fungal / diagnosis*
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Lung Diseases, Fungal / drug therapy
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Male
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Mining
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Occupational Diseases / diagnosis*
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Occupational Diseases / drug therapy
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Tuberculosis, Miliary / diagnosis
Substances
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Antifungal Agents
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Antitubercular Agents
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Amphotericin B