Characterization of qnrB-like genes in Citrobacter species of the American Type Culture Collection

Antimicrob Agents Chemother. 2013 Jun;57(6):2863-6. doi: 10.1128/AAC.02396-12. Epub 2013 Mar 25.

Abstract

Among five American Type Culture Collection (ATCC) Citrobacter strains, qnrB60 in Citrobacter freundii ATCC 6879, an isolate from the preantibiotic era, and qnrB61 in Citrobacter braakii ATCC 51113(T), a type strain belonging to the C. freundii complex, were identified. Meanwhile, a truncated qnrB-like pseudogene was identified in C. freundii ATCC 8090(T) and ATCC 43864. No qnrB-like sequence was found in Citrobacter koseri ATCC 27028(T). These findings underscore the close relationship between this species and qnrB.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / genetics
  • Citrobacter / classification*
  • Citrobacter / drug effects*
  • Citrobacter / genetics
  • Drug Resistance, Bacterial / genetics*
  • Genes, Bacterial*
  • Humans
  • Molecular Sequence Data
  • Plasmids / genetics
  • Quinolones / pharmacology*
  • Sequence Analysis, DNA

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Quinolones

Associated data

  • GENBANK/AB734052
  • GENBANK/AB734053
  • GENBANK/AB734054
  • GENBANK/AB734055
  • GENBANK/AB734056