Serious skin toxicity with the combination of BRAF inhibitors and radiotherapy

J Clin Oncol. 2013 May 1;31(13):e220-2. doi: 10.1200/JCO.2012.44.4265. Epub 2013 Mar 25.
No abstract available

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Chemoradiotherapy / adverse effects
  • Dermatitis, Contact / etiology*
  • Female
  • Humans
  • Imidazoles / adverse effects*
  • Indoles / adverse effects*
  • Male
  • Melanoma / drug therapy
  • Melanoma / pathology
  • Melanoma / radiotherapy
  • Melanoma / therapy*
  • Middle Aged
  • Oximes / adverse effects*
  • Protein Kinase Inhibitors / adverse effects*
  • Proto-Oncogene Proteins B-raf / antagonists & inhibitors*
  • Proto-Oncogene Proteins B-raf / genetics
  • Radiation Injuries / chemically induced
  • Radiation Injuries / etiology*
  • Radiotherapy, Conformal / adverse effects
  • Skin Neoplasms / drug therapy
  • Skin Neoplasms / pathology
  • Skin Neoplasms / radiotherapy
  • Skin Neoplasms / therapy
  • Sulfonamides / adverse effects*
  • Vemurafenib

Substances

  • Imidazoles
  • Indoles
  • Oximes
  • Protein Kinase Inhibitors
  • Sulfonamides
  • Vemurafenib
  • BRAF protein, human
  • Proto-Oncogene Proteins B-raf
  • dabrafenib