T1 and T2 relaxation times on gadolinium-diethylenetriaminepentaacetic acid enhanced magnetic resonance images of brain tumors

Tohoku J Exp Med. 1990 Feb;160(2):145-8. doi: 10.1620/tjem.160.145.

Abstract

MRI of brain tumors was performed with CPMG pulse sequence, and T1 and T2 relaxation times were measured before and after the administration of 0.1 mmol/kg Gd-DTPA. T1 and T2 became significantly shorter than before with the T1 shortening being about twice the T2's. Three types of T2 shortening were classified by the difference in the intra-tumoral transport of Gd-DTPA in the time-course study after the administration. Transportal activity of Gd-DTPA seemed to be reflected by the physiologic viability of tumor suggested by pre-contrast T2.

MeSH terms

  • Adolescent
  • Adult
  • Brain Neoplasms / diagnosis*
  • Child
  • Child, Preschool
  • Contrast Media
  • Female
  • Gadolinium DTPA
  • Glioma / diagnosis*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Meningeal Neoplasms / diagnosis*
  • Meningioma / diagnosis*
  • Middle Aged
  • Organometallic Compounds*
  • Pentetic Acid*

Substances

  • Contrast Media
  • Organometallic Compounds
  • Pentetic Acid
  • Gadolinium DTPA