Prosthetic valve endocarditis and bloodstream infection due to Mycobacterium chimaera

J Clin Microbiol. 2013 Jun;51(6):1769-73. doi: 10.1128/JCM.00435-13. Epub 2013 Mar 27.

Abstract

Prosthetic valve endocarditis (PVE) due to fast-growing nontuberculous mycobacteria (NTM) has been reported anecdotally. Reports of PVE with slowly growing NTM, however, are lacking. We present here one case of PVE and one case of bloodstream infection caused by Mycobacterium chimaera. Randomly amplified polymorphic DNA (RAPD)-PCR indicated a relatedness of the two M. chimaera strains. Both patients had heart surgery 2 years apart from each other. A nosocomial link was not detected.

Publication types

  • Case Reports

MeSH terms

  • DNA, Bacterial / genetics
  • Endocarditis, Bacterial / diagnosis*
  • Endocarditis, Bacterial / microbiology
  • Genotype
  • Humans
  • Male
  • Middle Aged
  • Molecular Typing
  • Mycobacterium Infections, Nontuberculous / diagnosis*
  • Mycobacterium Infections, Nontuberculous / microbiology
  • Nontuberculous Mycobacteria / classification
  • Nontuberculous Mycobacteria / genetics
  • Nontuberculous Mycobacteria / isolation & purification*
  • Prosthesis-Related Infections / diagnosis*
  • Prosthesis-Related Infections / microbiology
  • Random Amplified Polymorphic DNA Technique

Substances

  • DNA, Bacterial